Searchable abstracts of presentations at key conferences in endocrinology

ea0047oc3 | Spotlight on Neuroendocrine tumours | Theranostics2016

Optimised production of 64Cu-SARTATE for a phase 1 clinical trial

Roselt Peter , Noonan Wayne , Jeffery Charmaine , Price Roger , Hedt Amos

A new radiopharmaceutical using the somatostatin analogue octreotide has been developed for use in humans. SARTATE consists of the novel bifunctional chelator, MeCOSar, conjugated to (Tyr3)-octreotate. MeCOSar is a superior chelator for copper over a wide pH range and at room temperature, which allows for SARTATE to be used as an imaging/therapy pair when radiolabelled with copper-64 and copper-67.4Cu-SARTATE was produced by radiola...